URIDYLYL-(3'-]5')-(5'-THIOURIDINE) - AN EXCEPTIONALLY BASE-LABILE DI-RIBONUCLEOSIDE PHOSPHATE ANALOG

被引：40

作者：

LIU, XH ^{[1
]}

REESE, CB ^{[1
]}

机构：

[1] UNIV LONDON KINGS COLL,DEPT CHEM,LONDON WC2R 2LS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 19期

关键词：

D O I：

10.1016/0040-4039(95)00495-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Like uridylyl-(3'-->5')-uridine (UpU), uridylyl-(3'-->5')-(5'-thiouridine) 2 both undergoes hydrolysis and isomerizes in aqueous acidic solution; however, it is very much more susceptible to hydrolysis than UpU under neutral and mildly basic conditions.

引用

页码：3413 / 3416

页数：4

共 11 条

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