THE EFFECT OF HEPATOCYTE GROWTH-FACTOR SCATTER FACTOR ON HUMAN HAIR FOLLICLE GROWTH

被引：43

作者：

JINDO, T

TSUBOI, R

IMAI, R

TAKAMORI, K

RUBIN, JS

OGAWA, H

机构：

[1] JUNTENDO UNIV,SCH MED,DEPT DERMATOL,BUNKYO KU,TOKYO 113,JAPAN

[2] NCI,CELLULAR & MOLEC BIOL LAB,BETHESDA,MD 20892

来源：

JOURNAL OF DERMATOLOGICAL SCIENCE | 1995年 / 10卷 / 03期

关键词：

HEPATOCYTE GROWTH FACTOR; CYTOKINE; ORGAN CULTURE; HUMAN HAIR GROWTH;

D O I：

10.1016/0923-1811(95)00429-V

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The effect of hepatocyte growth factor/scatter factor (HGF/SF) on human hair follicle growth was examined using: a serum-free organ culture system. The DNA synthesis in human hair follicles and elongation of the hair shaft were measured subsequent to the follicle isolation and culture at 31 degrees C in 95%, O-2-5%, CO2 for 72 h. Results showed that HGF/SF significantly increased H-3-thymidine (P < 0.001) incorporation and hair follicle length (P < 0.05). The effect of HGF/SF was dose-dependent with a maximal stimulation at 10 ng/ml.

引用

页码：229 / 232

页数：4

共 19 条

[1] MINOXIDIL STIMULATES MOUSE VIBRISSAE FOLLICLES IN ORGAN-CULTURE [J].