HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE DEFICIENCY - ASSOCIATION OF REDUCED CATALYTIC ACTIVITY WITH REDUCED LEVELS OF IMMUNOLOGICALLY DETECTABLE ENZYME PROTEIN

被引：31

作者：

UPCHURCH, KS

LEYVA, A

ARNOLD, WJ

HOLMES, EW

KELLEY, WN

机构：

[1] DUKE UNIV,MED CTR,DEPT BIOCHEM,DURHAM,NC 27710

[2] DUKE UNIV,MED CTR,DEPT MED,DIV RHEUMAT & GENET DIS,DURHAM,NC 27710

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1975年 / 72卷 / 10期

关键词：

D O I：

10.1073/pnas.72.10.4142

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：4142 / 4146

页数：5

共 17 条

[1]

ARNOLD WJ, 1971, J BIOL CHEM, V246, P7398

[2] HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE - CHARACTERISTICS OF MUTANT ENZYME IN ERYTHROCYTES FROM PATIENTS WITH LESCH-NYHAN SYNDROME [J].

ARNOLD, WJ ;

MEADE, JC ;

KELLEY, WN .

JOURNAL OF CLINICAL INVESTIGATION, 1972, 51 (07) :1805-&

[3] RESTORATION OF HYPOXANTHINE PHOSPHORIBOSYL TRANSFERASE-ACTIVITY IN MOUSE-1R CELLS AFTER FUSION WITH CHICK-EMBRYO FIBROBLASTS [J].

BAKAY, B ;

CROCE, CM ;

KOPROWSKI, H ;

NYHAN, WL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (07) :1998-2002

[4] MUTATIONS AFFECTING STRUCTURE OF HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE IN CULTURED CHINESE-HAMSTER CELLS [J].

BEAUDET, AL ;

ROUFA, DJ ;

CASKEY, CT .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (02) :320-324

[5] SELECTIVE DEGRADATION OF ABNORMAL PROTEINS IN MAMMALIAN TISSUE-CULTURE CELLS [J].

CAPECCHI, MR ;

CAPECCHI, NE ;

HUGHES, SH ;

WAHL, GM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1974, 71 (12) :4732-4736

[6]

FIJIMOTO WY, 1970, P NAT ACAD SCI US, V65, P577

[7]

KELLEY WN, 1971, J BIOL CHEM, V246, P2953

[8]

KELLEY WN, 1973, FED PROC, V32, P1656

[9] A SPECIFIC ENZYME DEFECT IN GOUT ASSOCIATED WITH OVERPRODUCTION OF URIC ACID [J].

KELLEY, WN ;

ROSENBLO.FM ;

HENDERSO.JF ;

SEEGMILL.JE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1967, 57 (06) :1735-+

[10] FAMILIAL DISORDER OF URIC ACID METABOLISM + CENTRAL NERVOUS SYSTEM FUNCTION [J].

LESCH, M ;

NYHAN, WL .

AMERICAN JOURNAL OF MEDICINE, 1964, 36 (04) :561-&

← 1 2 →