PROTEIN MODULES

被引：192

作者：

BARON, M

NORMAN, DG

CAMPBELL, ID

机构：

[1] M. Baron, D.G. Norman and I.D. Campbell are, the Department of Biochemistry, Oxford, OX1 3QU, South Parks Road

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1991年 / 16卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0968-0004(91)90009-K

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

As the database of protein sequences grows it is becoming apparent that many proteins are constructed from relatively few modular units that appear many times. Determination of the three-dimensional structure of such modules by NMR has been possible due to their production in relatively large quantities by recombinant DNA techniques. The knowledge gained about the structure of individual modules can then be used to predict their properties in a variety of intact proteins.

引用

页码：13 / 17

页数：5

共 30 条

[1] SCANNING TUNNELING MICROSCOPY IN BIOTECHNOLOGY [J].

ARSCOTT, PG ;

BLOOMFIELD, VA .

TRENDS IN BIOTECHNOLOGY, 1990, 8 (06) :151-156

[2] SOLUTION STRUCTURE OF THE KRINGLE-4 DOMAIN FROM HUMAN PLASMINOGEN BY H-1 NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY AND DISTANCE GEOMETRY [J].

ATKINSON, RA ;

WILLIAMS, RJP .

JOURNAL OF MOLECULAR BIOLOGY, 1990, 212 (03) :541-552

[3] STRUCTURE OF CALMODULIN REFINED AT 2.2 A RESOLUTION [J].

BABU, YS ;

BUGG, CE ;

COOK, WJ .

JOURNAL OF MOLECULAR BIOLOGY, 1988, 204 (01) :191-204

[4]

BARLOW P, IN PRESS BIOCHEMISTR

[5] STRUCTURE OF THE FIBRONECTIN TYPE 1 MODULE [J].

BARON, M ;

NORMAN, D ;

WILLIS, A ;

CAMPBELL, ID .

NATURE, 1990, 345 (6276) :642-646

[6]

BARON M, 1990, PROTEIN PRODUCTION B, P49

[7] SEQUENCE OF AN UNUSUALLY LARGE PROTEIN IMPLICATED IN REGULATION OF MYOSIN ACTIVITY IN C-ELEGANS [J].

BENIAN, GM ;

KIFF, JE ;

NECKELMANN, N ;

MOERMAN, DG ;

WATERSTON, RH .

NATURE, 1989, 342 (6245) :45-50

[8] ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE-1 - AN INDUCIBLE RECEPTOR FOR NEUTROPHILS RELATED TO COMPLEMENT REGULATORY PROTEINS AND LECTINS [J].

BEVILACQUA, MP ;

STENGELIN, S ;

GIMBRONE, MA ;

SEED, B .

SCIENCE, 1989, 243 (4895) :1160-1165

[9] STRUCTURE-FUNCTION-RELATIONSHIPS IN EPIDERMAL GROWTH-FACTOR (EGF) AND TRANSFORMING GROWTH FACTOR-ALPHA (TGF-ALPHA) [J].

CAMPBELL, ID ;

BARON, M ;

COOKE, RM ;

DUDGEON, TJ ;

FALLON, A ;

HARVEY, TS ;

TAPPIN, MJ .

BIOCHEMICAL PHARMACOLOGY, 1990, 40 (01) :35-40

[10] THE SOLUTION STRUCTURE OF HUMAN EPIDERMAL GROWTH-FACTOR [J].

COOKE, RM ;

WILKINSON, AJ ;

BARON, M ;

PASTORE, A ;

TAPPIN, MJ ;

CAMPBELL, ID ;

GREGORY, H ;

SHEARD, B .

NATURE, 1987, 327 (6120) :339-341

← 1 2 3 →