UTILITY OF CYCLODEXTRIN IN MOBILE PHASE FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF BUFADIENOLIDES

被引：17

作者：

SHIMADA, K

KURATA, Y

OE, T

机构：

[1] Faculty of Pharmaceutical Sciences, Kanazawa University, Kanazawa 920

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1990年 / 13卷 / 03期

关键词：

D O I：

10.1080/01483919008051801

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The chromatographic behavior of bufadienolides including conjugates was examined by the addition of Y-cyclodextrin to the mobile phase in reversed-phase high-performance liquid chromatography. The capacity factor of sulfate or glucuronide was decreased sharply by the additive. The separation of bufadienolides, unseparable under the usual method, was much improved by the addition of y-cyclodextrin. © 1990, Taylor & Francis Group, LLC. All rights reserved.

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页码：493 / 504

页数：12

相关论文

共 12 条

[1] CYCLODEXTRIN BONDED PHASES FOR THE LIQUID-CHROMATOGRAPHIC SEPARATION OF OPTICAL, GEOMETRICAL, AND STRUCTURAL ISOMERS [J].

ARMSTRONG, DW ;

DEMOND, W .

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1984, 22 (09) :411-415

[2] NEW SENSITIVE DERIVATIZATION OF HYDROXYSTEROIDS FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH FLUORESCENCE DETECTION [J].

GOTO, J ;

GOTO, N ;

SHAMSA, F ;

SAITO, M ;

KOMATSU, S ;

SUZAKI, K ;

NAMBARA, T .

ANALYTICA CHIMICA ACTA, 1983, 147 (MAR) :397-400

[3] SEPARATION OF BUFOTALIN AND CINOBUFOTALIN BY PREPARATIVE LIQUID-CHROMATOGRAPHY [J].

INOUE, M ;

KAMANO, Y ;

PETTIT, GR ;

SMITH, CR .

JOURNAL OF LIQUID CHROMATOGRAPHY, 1987, 10 (11) :2453-2460

[4] STUDIES ON STEROIDS .114. SEPARATION OF CARDIOTONIC STEROID CONJUGATES BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

SHIMADA, K ;

HASEGAWA, M ;

HASEBE, K ;

FUJII, Y ;

NAMBARA, T .

JOURNAL OF CHROMATOGRAPHY, 1976, 124 (01) :79-87

[5]

SHIMADA K, 1976, CHEM PHARM BULL, V24, P2995

[6] APPLICATION OF INCLUSION CHROMATOGRAPHY TO THE DETERMINATION OF INVITRO METABOLITES OF ESTRIOL [J].

SHIMADA, K ;

MASUE, T ;

CHIBA, H .

JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1989, 27 (09) :557-560

[7]

SHIMADA K, 1977, CHEM PHARM BULL, V25, P714

[8] UTILITY OF CYCLODEXTRIN IN MOBILE PHASE FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF CARDENOLIDES [J].

SHIMADA, K ;

OE, T ;

KANNO, C ;

NAMBARA, T .

ANALYTICAL SCIENCES, 1988, 4 (04) :377-380

[9] RETENTION BEHAVIOR OF CARDIAC STEROIDS USING CYCLODEXTRIN IN THE MOBILE PHASE IN HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

SHIMADA, K ;

OE, T ;

HIROSE, Y ;

KOMINE, Y .

JOURNAL OF CHROMATOGRAPHY, 1989, 478 (02) :339-347

[10] CHROMATOGRAPHIC BEHAVIOR OF BILE-ACIDS USING CYCLODEXTRIN IN MOBILE PHASE OF HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY [J].

SHIMADA, K ;

KOMINE, Y ;

OE, T .

JOURNAL OF LIQUID CHROMATOGRAPHY, 1989, 12 (04) :491-500