AUTORADIOGRAPHIC LOCALIZATION OF ALPHA-2-ADRENOCEPTORS IN CHICK BRAIN

被引：16

作者：

FERNANDEZLOPEZ, A

DELARCO, C

GONZALEZ, AM

GOMEZ, T

CALVO, P

PAZOS, A

机构：

[1] UNIV CANTABRIA,DEPT PHYSIOL & PHARMACOL,PHARMACOL UNIT,E-39011 SANTANDER,SPAIN

[2] UNIV LEON,DEPT CELLULAR BIOL & ANAT,LEON,SPAIN

[3] UNIV LEON,DEPT PHYSIOL & PHARMACOL,LEON,SPAIN

来源：

NEUROSCIENCE LETTERS | 1990年 / 120卷 / 01期

关键词：

Autoradiography; Chick brain; Hyperstriatum; Visual pathway; [!sup]3[!/sup]H]UK 14304; α[!sub]2[!/sub]-Adrenoceptor;

D O I：

10.1016/0304-3940(90)90177-B

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

α2-Adrenoceptors were localized in the chick brain by 'in vitro' receptor autoradiography using [3H]UK 14304 as a ligand. High or very high densities of binding sites were found in the hyperstriatum, tuberculum olfactorium, hypothalamic nuclei, tectum opticum and some medullary nuclei. Comparatively, intermediate densities were observed over the thalamic nuclei and locus ceruleus, among others. Low densities of α2-adrenoceptors were detected in the paleostriatum, hippocampus and cerebellum. Our data indicate that α2-adrenoceptors in the chick brain present similar properties and homologous anatomical distribution to those reported in mammalian brain. © 1990.

引用

页码：97 / 100

页数：4

共 17 条

[1] ADRENOCEPTORS [J].