VISUAL RATING OF MAGNETIC-RESONANCE IMAGES OF HUMAN CEREBROSPINAL-FLUID SPACES AND WHITE BRAIN MATTER - RELATION TO SEX AND AGE IN HEALTHY-VOLUNTEERS

被引：7

作者：

AGARTZ, I

MARIONS, O

SAAF, J

WAHLUND, LO

WETTERBERG, L

机构：

[1] Karolinska Institute, Department of Psychiatry, St. Göran's Hospital

[2] Department of Radiology, Söder Hospital

来源：

MAGNETIC RESONANCE IMAGING | 1992年 / 10卷 / 01期

关键词：

MAGNETIC RESONANCE IMAGING; LOW FIELD; NORMAL BRAIN; HEALTHY CONTROLS; CSF SPACES; WHITE MATTER LESIONS;

D O I：

10.1016/0730-725X(92)90383-B

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The size of the cerebrospinal fluid spaces and the occurrence of white matter lesions were estimated from the intracranial volumes of 76 apparently healthy adult volunteers of different ages using 0.02-T/0.8-MHz magnetic resonance imaging. A relation between the occurrence of white matter lesions and the size of cerebrospinal fluid spaces independent of age could not be demonstrated. In men, white matter changes were more numerous and lateral ventricular size was larger, but sex differences were not statistically significant except for lateral ventricular size. The results confirm that age is the most significant parameter correlated with alterations in brain anatomy over time. Body mass and other clinical parameters were not influential factors in the present material.

引用

页码：135 / 142

页数：8

共 32 条

[1]

Earnest, Heaton, Wilkinson, Manke, Cortical atrophy, ventricular enlargement and intellectual impairment in the aged, Neurology, 29, pp. 1138-1143, (1979)

[2]

Yerby, Sundsten, Larson, Wu, Sumi, A new method of measuring brain atrophy: The effect of aging in its application for diagnosing dementia, Neurology, 35, pp. 1316-1320, (1985)

[3]

Pfefferbaum, Zatz, Jernigan, Computer-interactive method for quantifying cerebrospinal fluid and tissue in brain CT scans: Effects of aging, J. Computer Assist. Tomogr., 10, pp. 571-578, (1986)

[4]

Koenig, Brown, Adams, Emerson, Harrison, Magnetic field dependence of 1/T1 of protons in tissue, Invest. Radiol., 19, pp. 76-81, (1984)

[5]

Agartz, Saaf, Wahlund, Wetterberg, T1 and T2 relaxation time estimates in the normal human brain, Radiology, 181, (1991)

[6]

Andreasen, Swayze, Flaum, Yates, Arndt, McChesney, Ventricular enlargement in schizophrenia evaluated with computed tomographic scanning. Effects of gender, age and stage of illness, Arch. Gen. Psychiatry, 47, pp. 1008-1015, (1990)

[7]

Kuskowska-Wolk, Rossner, Prevalence of obesity in Sweden: Cross-sectional study of a representative adult population, J. Internal Med., 227, pp. 241-246, (1990)

[8]

Gyldensted, Measurements of the normal ventricular system and hemispheric sulci of 100 adults with computed tomography, Neuroradiology, 14, pp. 183-192, (1977)

[9]

Barron, Jacobs, Kinkel, Changes in size of normal lateral ventricles during aging determined by computerized tomography, Neurology, 26, pp. 1011-1013, (1976)

[10]

Lim, Zipursky, Murphy, Pfefferbaum, In vivo quantification of the limbic system using MRI: Effects of normal aging, Psychiatry Res.: Neuroimaging, 35, pp. 15-26, (1990)

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