NEUROENDOCRINE REGULATION OF GROWTH-HORMONE SECRETION IN SHEEP .6. INTRACEREBROVENTRICULAR ADMINISTRATION OF GALANIN

被引：13

作者：

SPENCER, GSG

BERRY, CJ

BASS, JJ

机构：

[1] Growth Physiology, Ruakura Agricultural Centre, Hamilton

来源：

NEUROREPORT | 1994年 / 5卷 / 04期

关键词：

GROWTH HORMONE; GALANIN; SHEEP;

D O I：

10.1097/00001756-199401120-00040

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

THE effects of intracerebroventricular (i.c.v.) administration of galanin on plasma growth hormone (GH) concentrations and its possible mechanism of action have been examined in sheep. Galanin administration icv resulted in a dose-dependent increase in plasma GH concentrations (p < 0.01). Concurrent administration of somatostatin (0.5 mu g kg(-1) i.v. over 30 min) caused a delay in the GH response to galanin, but did not inhibit the GH release. These data show that galanin can stimulate GH release in sheep, but the mechanism through which this effect is mediated remains unclear.

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页码：522 / 524

页数：3

相关论文

共 17 条

[1]

BJORKSTRAND E, 1993, NEUROREPORT, V4, P10

[2] THE NEUROPHYSIOLOGICAL REGULATION OF GROWTH-HORMONE SECRETION [J].

BUONOMO, FC ;

BAILE, CA .

DOMESTIC ANIMAL ENDOCRINOLOGY, 1990, 7 (04) :435-450

[3] EPINEPHRINE MEDIATES THE GROWTH HORMONE-RELEASING EFFECT OF GALANIN IN INFANT RATS [J].

CELLA, SG ;

LOCATELLI, V ;

DEGENNARO, V ;

BONDIOLOTTI, GP ;

PINTOR, C ;

LOCHE, S ;

PROVEZZA, M ;

MULLER, EE .

ENDOCRINOLOGY, 1988, 122 (03) :855-859

[4] CCK-OCTAPEPTIDE INJECTED IN CSF DECREASES MEAL SIZE AND DAILY FOOD-INTAKE IN SHEEP [J].

DELLAFERA, MA ;

BAILE, CA .

PEPTIDES, 1980, 1 (01) :51-54

[5] GALANIN LACKS BINDING-SITES IN THE PORCINE PITUITARY AND HAS NO DETECTABLE EFFECT ON OXYTOCIN AND VASOPRESSIN RELEASE FROM RAT NEUROSECRETORY ENDINGS [J].

GAYMANN, W ;

FALKE, N .

NEUROSCIENCE LETTERS, 1990, 112 (01) :114-119

[6] ON THE ROLE OF THE PEPTIDE GALANIN IN REGULATION OF GROWTH-HORMONE SECRETION [J].

HULTING, AL ;

MEISTER, B ;

CARLSSON, L ;

HILDING, A ;

ISAKSSON, O .

ACTA ENDOCRINOLOGICA, 1991, 125 (05) :518-525

[7] EVIDENCE FOR INVOLVEMENT OF ENDOGENOUS SOMATOSTATIN IN THE GALANIN-INDUCED GROWTH-HORMONE SECRETION IN CHILDREN [J].

LOCHE, S ;

VISTA, N ;

GHIGO, E ;

VANNELLI, S ;

ARVAT, E ;

BENSO, L ;

CORDA, R ;

CELLA, SG ;

MULLER, EE ;

PINTOR, C .

PEDIATRIC RESEARCH, 1990, 27 (04) :405-407

[8] GALANIN IS A PHYSIOLOGICAL REGULATOR OF SPONTANEOUS PULSATILE SECRETION OF GROWTH-HORMONE IN THE MALE-RAT [J].

MAITER, DM ;

HOOI, SC ;

KOENIG, JI ;

MARTIN, JB .

ENDOCRINOLOGY, 1990, 126 (02) :1216-1222

[9] POSSIBLE MECHANISMS INVOLVED IN GROWTH-HORMONE SECRETION INDUCED BY GALANIN IN THE RAT [J].

MURAKAMI, Y ;

KATO, Y ;

SHIMATSU, A ;

KOSHIYAMA, H ;

HATTORI, N ;

YANAIHARA, N ;

IMURA, H .

ENDOCRINOLOGY, 1989, 124 (03) :1224-1229

[10] GALANIN COEXISTS WITH VASOPRESSIN IN THE NORMAL RAT HYPOTHALAMUS AND GALANINS SYNTHESIS IS INCREASED IN THE BRATTLEBORO (DIABETES-INSIPIDUS) RAT [J].

ROKAEUS, A ;

YOUNG, WS ;

MEZEY, E .

NEUROSCIENCE LETTERS, 1988, 90 (1-2) :45-50