ENANTIOMERIC SEPARATION OF 5-FLUORO-DOPA AND 6-FLUORO-D/L-DOPA (3,4-DIHYDROXYPHENYLALANINE)

被引：2

作者：

MADER, T ^{[1
]}

ARGENTINI, M ^{[1
]}

WIESE, C ^{[1
]}

WEINREICH, R ^{[1
]}

机构：

[1] PAUL SCHERRER INST,INST MED RADIOBIOL,CH-5232 VILLIGEN PSI,SWITZERLAND

来源：

FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY | 1992年 / 343卷 / 03期

关键词：

D O I：

10.1007/BF00322383

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

To study the metabolism of 5-Fluoro- and 6-Fluoro-L- and -D-dopa in organotypic brain cell cultures, the enantiomers of 5-Fluoro- and 6-Fluoro-D/L-dopa were separated. Commercial chiral columns CHIRALPAK WH showed excellent separation results for this system. The separation remained constant for more than 60 consecutive runs which implies the use of this column also for preparative purposes.

引用

页码：324 / 325

页数：2

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