A REVIEW OF PROTON-BEAM RADIATION-THERAPY

被引:102
作者
MILLER, DW
机构
[1] Department of Radiation Medicine, Loma Linda University Medical Center, Loma Linda, California
关键词
PROTONS; THERAPY HISTORY; TREATMENT DOSIMETRY; PROTON SYSTEMS; PROTON MICRODOSIMETRY;
D O I
10.1118/1.597435
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Beams of protons have been used for radiation treatment for approximately 40 years. This paper provides a short summary of activities from institutions that have contributed to the field over this period. The paper reviews some of the basic interactions of protons with matter that are relevant to radiation treatment and summarizes current knowledge pertaining to the response of biological systems to proton beam radiation. The technical means of producing and delivering proton treatment beams are discussed along with examples of the implementation of these methods at treatment facilities around the world. Finally, the clinical dosimetry of proton beams is summarized and sample data are presented.
引用
收藏
页码:1943 / 1954
页数:12
相关论文
共 86 条
[1]  
ABROSIMOV NK, 1985, P ACAD SCI USSR, V5, P84
[2]   PROGRESS IN LOW-LET HEAVY PARTICLE THERAPY - INTRACRANIAL AND PARACRANIAL TUMORS AND UVEAL MELANOMAS [J].
AUSTINSEYMOUR, M ;
MUNZENRIDER, JE ;
GOITEIN, M ;
GENTRY, R ;
GRAGOUDAS, E ;
KOEHLER, AM ;
MCNULTY, P ;
OSBORNE, E ;
RYUGO, DK ;
SEDDON, J ;
URIE, M ;
VERHEY, L ;
SUIT, HD .
RADIATION RESEARCH, 1985, 104 (02) :S219-S226
[3]  
BERGER MJ, 1993, PENETRATION PROTON B, V1
[4]   CURRENT DEVELOPMENTS IN PROTON THERAPY - A REVIEW [J].
BONNETT, DE .
PHYSICS IN MEDICINE AND BIOLOGY, 1993, 38 (10) :1371-1392
[5]  
BONNETT DE, UNPUB BR J RADIOL
[6]   INTRODUCTION TO USE OF PROTONS AND HEAVY-IONS IN RADIATION-THERAPY - HISTORICAL-PERSPECTIVE [J].
BOONE, MLM ;
LAWRENCE, JH ;
CONNOR, WG ;
MORGADO, R ;
HICKS, JA ;
BROWN, RC .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1977, 3 :65-69
[7]  
BRIDIER A, 1991, JUL P NIRS INT WORKS, P166
[8]  
CASTRO JR, 1985, CURRENT CONSIDERATIO, pS263
[9]  
Chauvel P, 1990, 2ND P EUR ACC C JUN, pS85
[10]   INSTRUMENTATION FOR TREATMENT OF CANCER USING PROTON AND LIGHT-ION BEAMS [J].
CHU, WT ;
LUDEWIGT, BA ;
RENNER, TR .
REVIEW OF SCIENTIFIC INSTRUMENTS, 1993, 64 (08) :2055-2122