MECHANICAL CONTROL OF REDOX ENTHALPY

被引：5

作者：

BRILL, AS

机构：

[1] Department of Physics, University of Virginia, Charlottesville, VA

来源：

MOLECULAR PHYSICS | 1995年 / 85卷 / 04期

关键词：

D O I：

10.1080/00268979500101431

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The change in elastic energy which accompanies transfer of an electron to an acceptor site in a protein is formulated. The sign and magnitude of this energy is found to depend upon the structural geometry to which the site is constrained by the stiffness of the protein. Through this enthalpy component, conditions which alter protein structure can contribute to the control of the oxidation-reduction equilibrium at the site. The difference between the total redox enthalpy and the elastic component is the electrostatic contribution. The formulation is applied to the electron acceptor site in the blue cupric protein azurin.

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页码：727 / 734

页数：8

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