EFFECT OF LIPID-MEMBRANES ON THE APPARENT PK OF THE LOCAL-ANESTHETIC TETRACAINE - SPIN LABEL AND TITRATION STUDIES

被引：87

作者：

SCHREIER, S

FREZZATTI, WA

ARAUJO, PS

CHAIMOVICH, H

CUCCOVIA, IM

机构：

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1984年 / 769卷 / 01期

关键词：

D O I：

10.1016/0005-2736(84)90027-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：231 / 237

页数：7

共 15 条

[1] MULTIPLE BINDING-SITES FOR LOCAL-ANESTHETICS IN MEMBRANES - CHARACTERIZATION OF THE SITES AND THEIR EQUILIBRIA BY DEUTERIUM NMR OF SPECIFICALLY DEUTERATED PROCAINE AND TETRACAINE [J].

BOULANGER, Y ;

SCHREIER, S ;

LEITCH, LC ;

SMITH, ICP .

CANADIAN JOURNAL OF BIOCHEMISTRY, 1980, 58 (10) :986-995

[2] MOLECULAR DETAILS OF ANESTHETIC-LIPID INTERACTION AS SEEN BY DEUTERIUM AND P-31 NUCLEAR MAGNETIC-RESONANCE [J].

BOULANGER, Y ;

SCHREIER, S ;

SMITH, ICP .

BIOCHEMISTRY, 1981, 20 (24) :6824-6830

[3] EFFECTS OF LOCAL ANESTHETICS ON LIPID MULTILAYERS A SPIN PROBE STUDY [J].

BUTLER, KW ;

SCHNEIDER, H ;

SMITH, ICP .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1973, 154 (02) :548-554

[4]

Chaimovich H., 1982, SOLUTION BEHAVIOR SU, V2, P949

[5] A REMARKABLE ENHANCEMENT OF THE RATE OF ESTER THIOLYSIS BY SYNTHETIC AMPHIPHILE VESICLES [J].

CUCCOVIA, IM ;

QUINA, FH ;

CHAIMOVICH, H .

TETRAHEDRON, 1982, 38 (07) :917-920

[6] SHAPE OF HYDROPHOBIC BARRIER OF PHOSPHOLIPID BILAYERS (EVIDENCE FOR WATER PENETRATION IN BIOLOGICAL-MEMBRANES) [J].

GRIFFITH, OH ;

DEHLINGER, PJ ;

VAN, SP .

JOURNAL OF MEMBRANE BIOLOGY, 1974, 15 (02) :159-192

[7] EFFECTS OF CHARGED DRUGS ON PHASE-TRANSITION TEMPERATURES OF PHOSPHOLIPID BILAYERS [J].

LEE, AG .

BIOCHIMICA ET BIOPHYSICA ACTA, 1978, 514 (01) :95-104

[8] HYDROPHOBIC ADSORPTION OF CHARGED MOLECULES TO BILAYER MEMBRANES - TEST OF APPLICABILITY OF STERN EQUATION [J].

MCLAUGHLIN, S ;

HARARY, H .

BIOCHEMISTRY, 1976, 15 (09) :1941-1948

[9]

NIELSEN JR, 1980, LIPIDS, V15, P481

[10]

RITCHIE JM, 1961, J PHARMACOL EXP THER, V133, P241

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