LIPASE CATALYZED REGIOSELECTIVE AND ENANTIOSELECTIVE HYDROLYSIS - MOLECULAR RECOGNITION PHENOMENON AND SYNTHESIS OF (R)-DIMORPHECOLIC ACID

被引：22

作者：

BHALERAO, UT

DASARADHI, L

NEELAKANTAN, P

FADNAVIS, NW

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 17期

关键词：

D O I：

10.1039/c39910001197

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Molecular recognition has been observed in hydrolysis of racemic esters of (E)-9-acetoxy-11-bromoundec-10-enoic acid by a lipase of Candida cylindracea (E.C. 3.1.1.3) where optically active (R-(E)-9-acetoxy-11-bromoundec-10-enoic acid [enantiomeric excess (e.e.) > 99%] was obtained which was used in synthesis of (R)-dimorphecolic acid.

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页码：1197 / 1198

页数：2

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