HIGH-DOSE CHEMOTHERAPY WITH AUTOLOGOUS MARROW TRANSPLANTATION IN FOLLICULAR LYMPHOMAS

被引:21
作者
COLOMBAT, P
BINET, C
LINASSIER, C
DESBOIS, I
LAMAGNERE, JP
BIRON, P
PHILIP, T
机构
[1] Department of Haematology and Oncology, CHU, Tours, Cedex
[2] Department of Bone Marrow Transplantation-CentreLeon, Berard-28, Lyon, Cedex
关键词
FOLLICULAR LYMPHOMAS; AUTOLOGOUS BONE MARROW TRANSPLANTATION;
D O I
10.3109/10428199209061555
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Twenty six adult patients with low grade nodular non Hodgkin's lymphoma (NHL) were treated with autologous bone marrow transplantation. Conditioning regimen was BEAM-BEAC in 15 patients and TBI + Cyclophosphamide in 11 patients. Twenty one patients were grafted with haematopoietic stem cells, 12 after bone marrow purging and five with peripheral blood stem cells (PBSC). Two patients were treated in CR1 of leukemic phase, six in PR 1 and eighteen in sensitive relapse. With a median follow-up of 30 months, the actuarial survival is 91% and actuarial event free survival 67% These data confirm some interest of ABMT in the treatment of low grade follicular NHL. © 1992 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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收藏
页码:3 / 6
页数:4
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