PERICARDIAC METASTASIS FROM ADVANCED GASTRIC-CANCER

被引：12

作者：

MORIYAMA, A ^{[1
]}

MURATA, I ^{[1
]}

KURODA, T ^{[1
]}

YOSHIKAWA, I ^{[1
]}

TABARU, A ^{[1
]}

OGAMI, Y ^{[1
]}

OTSUKI, M ^{[1
]}

机构：

[1] UNIV OCCUPAT & ENVIRONM HLTH,SCH MED,DEPT INTERNAL MED 3,YAHATANISHI KU,KITAKYUSHU,FUKUOKA 807,JAPAN

来源：

JOURNAL OF GASTROENTEROLOGY | 1995年 / 30卷 / 04期

关键词：

PERICARDIAC METASTASIS; GASTRIC CANCER; CHEMOTHERAPY;

D O I：

10.1007/BF02347569

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A 64-year-old man complaining of anterior chest pain, weight loss, and neck tumors was found to have advanced gastric cancer with pleuritis carcinomatosa and multiple lymph node and bone metastases. The patient was treated with combination chemotherapy consisting of mitomycin C (MMC), tegafur (UFT), and lentinan, and then with MMC and 5-fluorouracil (5FU) instillation into the pleural spaces after pleural drainage. With these treatments, the primary tumors and cancerous ulcers of the stomach improved markedly, and the lymph node enlargement and pleural effusion disappeared completely. Afterwards pericardiac metastasis complicated by cardiac tamponade occurred, but repeated pericardiocentesis and administration of MMC into the pericardiac cavity effectively eliminated the effusion. These treatments appeared potentially useful for advanced gastric cancer with generalized metastases including pericardiac involvement. However, the patient died of cardiac tamponade with massive pericardiac bleeding, probably due to the repeated pericardiocentesis and/or the administration of anticancer drugs.

引用

页码：512 / 516

页数：5

共 15 条

[1]

Hanfling S.M., Metastatic cancer to the heart. Review of the literature and report of 127 cases, Circulation, 22, pp. 473-483, (1960)

[2]

Edward C., Klatt M.D., Daniel R., Cardiac metastases, Cancer, 65, pp. 1456-1459, (1990)

[3]

Mukai K., Shinkai T., Tominaga K., Et al., The incidence of secondary tumors of the heart and pericardium: A 10-year study, Jpn J Clin Oncol, 18, pp. 195-201, (1988)

[4]

Nakayama R., Yoneyama T., Takatani O., Et al., A study of metastatic tumors to the heart, pericardium and great vessels, Jpn Heart J, 7, pp. 227-234, (1966)

[5]

Tabata Y., Nakato H., Nakamura Z., Et al., Metastatic cancer to the heart: A clinicopathological analysis of 64 autopsy cases (in Japanese with English abstract), Kokyu to Junkan (Respiration and Circulation), 31, pp. 569-573, (1983)

[6]

Skhvatsabaja L.V., Secondary malignant lesions of the heart and pericardium in neoplastic disease, Oncology, 43, pp. 103-106, (1986)

[7]

Kline I.K., Cardiac lymphatic involvement by metastatic tumor, Cancer, 29, pp. 799-808, (1972)

[8]

Lamberta F., Nareff M.J., Schwab J., Metastatic carcinoma of the pericardium, CHEST Journal, 19, pp. 528-536, (1951)

[9]

Meigham S.S., Dick A., Malignant disease of the pericardium: Report of a case, Glasgow Med J, 150, pp. 324-326, (1951)

[10]

Steven R.A., Heart tumor: Report of a case, Am Heart J, 30, pp. 411-415, (1945)

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