ANTIGENIC COMPARISON OF LELYSTAD VIRUS AND SWINE INFERTILITY AND RESPIRATORY SYNDROME (SIRS) VIRUS

被引:181
作者
WENSVOORT, G
DEKLUYVER, EP
LUIJTZE, EA
DENBESTEN, A
HARRIS, L
COLLINS, JE
CHRISTIANSON, WT
CHLADEK, D
机构
[1] Department of Virology, Central Veterinary Institute, Lelystad
[2] Boehringer Ingelheim Animal Health, St. Joseph
[3] Department of Veterinary Diagnostic Medicine, University of Minnesota, St. Paul
[4] Department of Clinical and Population Sciences, University of Minnesota, St. Paul
关键词
D O I
10.1177/104063879200400203
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
This study reports the antigenic relatedness of isolates of Lelystad virus collected in the Netherlands, Germany, and the United States. The binding of antibodies directed against these isolates was tested in a set of field sera collected during outbreaks of porcine epidemic abortion and respiratory syndrome in Europe and outbreaks of swine infertility and respiratory syndrome (SIRS) in North America. Two sets of sera from pigs experimentally infected with Lelystad virus or SIRS virus were also tested. Although all 7 isolates reacted with anti-Lelystad virus sera, antigenic variation was considerable. The 4 European isolates resembled each other closely, but differed from the American isolates, and the 3 American isolates differed antigenically from each other. To reliably diagnose Lelystad virus infection, a common antigen must first be identified.
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收藏
页码:134 / 138
页数:5
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