FK-506 - AN IMMUNOSUPPRESSANT FOR THE 1990S

被引：61

作者：

MACLEOD, AM ^{[1
]}

THOMSON, AW ^{[1
]}

机构：

[1] UNIV ABERDEEN,SCH MED,DEPT PATHOL,IMMUNOPATHOL LAB,ABERDEEN AB9 2ZD,SCOTLAND

来源：

LANCET | 1991年 / 337卷 / 8732期

关键词：

D O I：

10.1016/0140-6736(91)93341-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The novel macrolide immunosuppressant FK 506 is a powerful and selective anti-T-cell agent which has a similar mode of action to that of cyclosporin. Clinical studies of FK 506 in liver allograft recipients indicate a lower risk/benefit ratio than with cyclosporin, and wider evaluation of FK 506 in transplant recipients is now under way in multicentre, prospective, controlled trials in both Europe and North America.

引用

页码：25 / 27

页数：3

共 49 条

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