A NOVEL SYNTHESIS OF DISUBSTITUTED 1,1-DIFLUORO-1-ALKENES BY USING 2,2,2-TRIFLUOROETHYL PARA-TOLUENESULFONATE AS A DIFLUOROVINYLIDENE UNIT

被引：32

作者：

ICHIKAWA, J ^{[1
]}

MORIYA, T ^{[1
]}

SONODA, T ^{[1
]}

KOBAYASHI, H ^{[1
]}

机构：

[1] KYUSHU UNIV, GRAD SCH ENGN SCI, DEPT MOLEC SCI & TECHNOL, KASUGA, FUKUOKA 816, JAPAN

来源：

CHEMISTRY LETTERS | 1991年 / 06期

关键词：

D O I：

10.1246/cl.1991.961

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

2,2,2-Trifluoroethyl p-toluenesulfonate is treated with lithium diisopropylamide and trialkylboranes successively to generate 1-alkyl-2,2-difluorovinylboranes, which in turn couple with aryl iodides in the presence of palladium catalyst and tetrabutylammonium fluoride to afford disubstituted 1,1-difluoro-1-alkenes in good yields.

引用

页码：961 / 964

页数：4

共 21 条

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