FRIEDEL CRAFTS COORDINATED PROCESSES - HIGHLY SELECTIVE SYNTHESIS OF HYDROXYNAPHTHOQUINONES

被引：23

作者：

SARTORI, G ^{[1
]}

BIGI, F ^{[1
]}

CANALI, G ^{[1
]}

MAGGI, R ^{[1
]}

CASNATI, G ^{[1
]}

TAO, XC ^{[1
]}

机构：

[1] CHINESE ACAD SCI, INST ORGAN CHEM, SHANGHAI 200032, PEOPLES R CHINA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 04期

关键词：

D O I：

10.1021/jo00056a014

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Simple preparation of ethyl 3-hydroxy-1,4-naphthoquinone-2-carboxylates 2 including heterocyclic analogs is accomplished by C-regioselective bis-acylation of aromatic and heteroaromatic beta-keto esters 1. Compounds 2 are readily hydrolyzed and decarboxylated to the corresponding 2-hydroxy-1,4-naphthoquinone derivatives 3.

引用

页码：840 / 843

页数：4

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