IS A RANDOM URINARY ALBUMIN CONCENTRATION A USEFUL SCREENING-TEST IN INSULIN-TREATED DIABETIC-PATIENTS

被引：3

作者：

BEATTY, OL ^{[1
]}

RITCHIE, CM ^{[1
]}

HADDEN, DR ^{[1
]}

KENNEDY, L ^{[1
]}

BELL, PM ^{[1
]}

ATKINSON, AB ^{[1
]}

机构：

[1] ROYAL VICTORIA HOSP,SIR GEORGE E CLARKE METAB UNIT,BELFAST BT12 6BA,NORTH IRELAND

来源：

IRISH JOURNAL OF MEDICAL SCIENCE | 1994年 / 163卷 / 09期

关键词：

D O I：

10.1007/BF02975038

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The debate continues on how to screen for microalbuminuria in clinical practice in patients with insulin-dependent diabetes mellitus. Our study assesses the value of a spot morning urine specimen obtained at a clinic visit. In 1984, as part of a randomised survey of our diabetes clinic, 43 of 249 patients with insulin treated diabetes mellitus, were found to have microalbuminuria (urinary albumin concentration 35-300 ug ml-1) on a spot morning urine sample. These subjects were compared with an age-matched control group from the 1984 cohort who did not have microalbuminuria. Eight years later, in the group with microalbuminuria, 10 had died compared to six in the control group (p = 0.17) with 62.5% of all deaths being from cardiovascular disease. In the group with microalbuminuria, 10 of 27 still had incipient nephropathy while five had progressed to nephropathy. In the group without microalbuminuria only three of 33 patients had progressed to microalbuminuria while none had progressed to nephropathy. In conclusion a spot morning urine sample is a useful screening test to identify patients at risk of progression to nephropathy.

引用

页码：406 / 409

页数：4

共 15 条

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