IS PARENTAL AGE-RELATED TO THE RISK OF ALZHEIMERS-DISEASE

被引：18

作者：

HOFMAN, A

VANDUIJN, CM

SCHULTE, W

TANJA, TA

HAAXMA, R

LAMERIS, AJ

SAAN, RJ

机构：

[1] Department of Epidemiology, Erasmus University, Medical School, 3000 DR Rotterdam

来源：

BRITISH JOURNAL OF PSYCHIATRY | 1990年 / 157卷

关键词：

D O I：

10.1192/bjp.157.2.273

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Advanced maternal and parental age were investigated as putative risk factors for AD in 198 clinically diagnosed Alzheimer patients and in 198 randomly selected healthy controls. No significant differences in average age of fathers and of mothers at birth of the subject were observed. The risk of AD was not significantly different across categories of maternal and parental age. The association with parental age was not different for sporadic and familial AD. These findings do not support the view of a maternal or paternal age effect on AD.

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页码：273 / 275

页数：3

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