A NOVEL LEISHMANICIDAL LABDANE FROM POLYALTHIA-MACROPODA

被引：30

作者：

RICHOMME, P

GODET, MC

FOUSSARD, F

TOUPET, L

SEVENET, T

BRUNETON, J

机构：

[1] FAC PHARM ANGERS, BIOCHIM & BIOL CELLULAIRE LAB, F-49100 ANGERS, FRANCE

[2] CRMPO, F-35045 RENNES, FRANCE

[3] INST CHIM SUBST NAT, CNRS, F-91190 GIF SUR YVETTE, FRANCE

来源：

PLANTA MEDICA | 1991年 / 57卷 / 06期

关键词：

POLYALTHIA-MACROPODA; ANNONACEAE; DITERPENE; LABDANE; LEISHMANICIDAL ACTIVITY;

D O I：

10.1055/s-2006-960204

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new diterpene, (4S,9R,10R) methyl 18-carboxy-labda-8,13(E)-diene-15-oate has been obtained from the stem barks of Polyalthia macropoda (Annonaceae). This labdanic derivative was identified on the basis of spectroscopic data and is biologically active against the promastigote Leishmania donovani donovani.

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页码：552 / 554

页数：3

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