SYNTHESIS OF PHENOLIC NATURAL-PRODUCTS USING PALLADIUM-CATALYZED COUPLING REACTIONS

被引：40

作者：

BATES, RW

GABEL, CJ

JI, JH

RAMADEVI, T

机构：

[1] Department of Chemistry, University of North Texas, Denton

来源：

TETRAHEDRON | 1995年 / 51卷 / 30期

关键词：

D O I：

10.1016/0040-4020(95)00441-A

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Derivatives of 2,4-diiodophenol are shown to undergo palladium catalyzed carbonylation and alkyne coupling reactions in excellent to moderate yield and high regioselectivity. The scope of these reactions is explored. Palladium catalyzed reactions are employed as the key steps in the synthesis of three phenolic natural products: Plicatin B, Drupanin and Eutypine.

引用

页码：8199 / 8212

页数：14

共 45 条

[1] AIDA M, 1994, HETEROCYCLES, V39, P847
[2] PALLADIUM-CATALYZED FORMYLATION OF ORGANIC HALIDES WITH CARBON-MONOXIDE AND TIN HYDRIDE
BAILLARGEON, VP
STILLE, JK
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (03) : 452 - 461
[3] THE SYNTHESIS OF PLICATIN-B VIA THE HECK REACTION
BATES, RW
GABEL, CJ
[J]. TETRAHEDRON LETTERS, 1993, 34 (22) : 3547 - 3550
[4] BATES RW, 1994, TETRAHEDRON LETT, V35, P693
[5] NATURALLY OCCURRING TERPENE DERIVATIVES .196. NEW DITERPENE AND OTHER COMPOUNDS FROM BACCHARIS SPECIES
BOHLMANN, F
KNAUF, W
KING, RM
ROBINSON, H
[J]. PHYTOCHEMISTRY, 1979, 18 (06) : 1011 - 1014
[6] NEW SESQUITERPENE ACIDS, SESQUITERPENE DIOL, FLAVANONES AND OTHER AROMATIC-COMPOUNDS FROM FLOURENSIA-HETEROLEPIS .198. NATURALLY OCCURRING TERPENE DERIVATIVES
BOHLMANN, F
JAKUPOVIC, J
[J]. PHYTOCHEMISTRY, 1979, 18 (07) : 1189 - 1194
[7] Brenans P, 1901, CR HEBD ACAD SCI, V132, P831
[8] ALPHA-REGIOSELECTIVITY IN PALLADIUM-CATALYZED ARYLATION OF ACYCLIC ENOL ETHERS
CABRI, W
CANDIANI, I
BEDESCHI, A
PENCO, S
SANTI, R
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (05) : 1481 - 1486
[9] CAHRI W, 1993, J ORG CHEM, V58, P7421
[10] CANDIANI I, 1993, SYNLETT, P269

← 1 2 3 4 5 →