ALPHA-TOCOPHEROL OXIDATION MEDIATED BY SUPEROXIDE ANION (O-2-) .2. IDENTIFICATION OF THE STABLE ALPHA-TOCOPHEROL OXIDATION-PRODUCTS

被引：16

作者：

HA, YL ^{[1
]}

CSALLANY, AS ^{[1
]}

机构：

[1] UNIV MINNESOTA,DEPT FOOD SCI & NUTR,ST PAUL,MN 55108

来源：

LIPIDS | 1992年 / 27卷 / 03期

关键词：

D O I：

10.1007/BF02536179

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The present paper describes the identification of two stable end products of alpha-tocopherol oxidation that were previously detected among the products of the reaction of alpha-tocopherol with superoxide anion (O2-) under aprotic conditions. One compound, previously designated compound A, was identified as trans-7-hydroxy-trans-8,8a-epoxy-alpha-tocopherone, and the other, designated compound B, was identified as cis-7-hydroxy-cis-8,8a-epoxy-alpha-tocopherone. It was also observed that under protic conditions (10% water in acetonitrile) the reaction of alpha-tocopherol with O2- did not produce compounds A and B, but rather alpha-tocopheryl quinone, alpha-tocopherol dimer, alpha-tocopherol dihydroxy dimer, and the previously designated compound C. Compound C was identified in the present study as alpha-tocopheryl-quinone-2,3-epoxide.

引用

页码：201 / 205

页数：5

共 25 条

[1] CHEMISTRY OF SINGLET OXYGEN .30. UNSTABLE PRIMARY PRODUCT OF TOCOPHEROL PHOTO-OXIDATION [J].