CYTOKINE PRODUCTION PROFILE OF EARLY THYMOCYTES AND THE CHARACTERIZATION OF A NEW CLASS OF CHEMOKINE

被引:22
作者
KELNER, GS [1 ]
ZLOTNIK, A [1 ]
机构
[1] DNAX RES INST MOLEC & CELLULAR BIOL INC,PALO ALTO,CA 94304
关键词
LYMPHOTACTIN; PRO-T CELLS; INTERLEUKINS;
D O I
10.1002/jlb.57.5.778
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
By using a variety of molecular techniques, we have characterized the cytokine profile of pro-T cells. During this characterization we cloned a novel cytokine that has chemotactic activities, We have designated this cytokine lymphotactin. The structural analysis, chromosomal location, and biological properties of lymphotactin provide strong evidence that this cytokine represents a new class of chemokine.
引用
收藏
页码:778 / 781
页数:4
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