PARVOVIRUS INFECTION CAUSING RED-CELL APLASIA AND LEUKOPENIA IN RHEUMATOID-ARTHRITIS

被引：10

作者：

KAMPER, AM

MALBRAIN, M

ZACHEE, P

CHEW, SL

机构：

[1] The Department of Internal Medicine, Stuivenberg General Hospital, Edegem

[2] Department of Endocrinology, St Bartholomew's Hospital, London

来源：

CLINICAL RHEUMATOLOGY | 1994年 / 13卷 / 01期

关键词：

PARVO VIRUS INFECTION; RED CELL APLASIA; LEUKOPENIA; RHEUMATOID ARTHRITIS;

D O I：

10.1007/BF02229883

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A case of acute parvovirus B19 infection causing fever, anaemia, leukopenia, and red cell aplasia, in a patient with chronic rheumatoid arthritis is described. The patient had received low doses of corticosteroids for several years, and a small dose of methotrexate recently. There was no evidence of haemolytic anaemia, iron deficiency or drug toxicity. Recovery was associated with the development of antibodies against parvovirus B19, and clearance of viraemia as detected by the polymerase chain reaction. Possible mechanisms for the development of leukopenia are discussed, but there was no evidence for haemophagocytosis.

引用

页码：129 / 131

页数：3

共 19 条

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