CORRELATION OF DYNAMIC-RESPONSES IN THE ON BIPOLAR NEURON AND THE B-WAVE OF THE ELECTRORETINOGRAM

被引：72

作者：

TIAN, N

SLAUGHTER, MM

机构：

[1] Departments of Biophysical Sciences and Ophthalmology, SUNY School of Medicine, Buffalo, NY 14214

来源：

VISION RESEARCH | 1995年 / 35卷 / 10期

关键词：

ELECTRORETINOGRAM; B-WAVE; BIPOLAR CELL; MULLER CELL; RETINA;

D O I：

10.1016/0042-6989(95)98715-L

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

2-Amino-4-phosphonobutyrate (APB) is known to selectively suppress the light response of ON bipolar cells in the vertebrate retina, and reduce the b-wave of the electroretinogram (ERG) as a consequence. Using slow drug application, the progressive effect of APB was used to compare the relative response amplitudes of the b-wave and the ON bipolar cell. Simultaneous ERG recordings and ON bipolar intracellular recordings were performed in the amphibian retina. The results indicate that there is a strong positive correlation between these two waveforms. This supports the possibility that the b-wave of the ERG is the direct result of ON bipolar cell activity.

引用

页码：1359 / 1364

页数：6

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