THE INFLUENCE OF THE SPARTEINE DEBRISOQUIN PHENOTYPE ON THE DISPOSITION OF FLECAINIDE

被引：64

作者：

MIKUS, G

GROSS, AS

BECKMANN, J

HERTRAMPF, R

GUNDERTREMY, U

EICHELBAUM, M

机构：

[1] DR MARGARETE FISCHERBOSCH INST KLIN PHARMAKOL,AUERBACHSTR 112,D-7000 STUTTGART 50,FED REP GER

[2] BUNDESGESUNDHEITSAMT,INST ARZNEIMITTEL,D-1000 BERLIN 33,FED REP GER

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 1989年 / 45卷 / 05期

关键词：

D O I：

10.1038/clpt.1989.73

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：562 / 567

页数：6

共 24 条

[1] PHARMACOKINETICS OF FLECAINIDE IN PATIENTS WITH MILD AND MODERATE RENAL-FAILURE COMPARED WITH PATIENTS WITH NORMAL RENAL-FUNCTION
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[2] FLECAINIDE HALF-LIFE PROLONGATION IN 2 PATIENTS WITH CONGESTIVE HEART-FAILURE AND COMPLEX VENTRICULAR ARRHYTHMIAS
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[3] APPLICATION OF A BONDED-PHASE EXTRACTION COLUMN FOR RAPID SAMPLE PREPARATION OF FLECAINIDE FROM HUMAN-PLASMA FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS - FLUORESCENCE OR ULTRAVIOLET DETECTION
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[4] METABOLISM OF FLECAINIDE
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[5] INFLUENCE OF THE DEFECTIVE METABOLISM OF SPARTEINE ON ITS PHARMACOKINETICS
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[J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1979, 16 (03) : 189 - 194
[6] POLYMORPHIC OXIDATION OF SPARTEINE AND DEBRISOQUINE - RELATED PHARMACOGENETIC ENTITIES
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[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1982, 31 (02) : 184 - 186
[7] ORAL FLECAINIDE PHARMACOKINETICS IN PATIENTS WITH IMPAIRED RENAL-FUNCTION
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BLAIR, AD
CUTLER, RE
KVAM, DC
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CONARD, GJ
[J]. JOURNAL OF CLINICAL PHARMACOLOGY, 1988, 28 (03) : 259 - 267
[8] EXTRACARDIAC ADVERSE-EFFECTS OF FLECAINIDE
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[J]. AMERICAN JOURNAL OF CARDIOLOGY, 1984, 53 (05) : B101 - B105
[9] CHARACTERIZATION OF THE COMMON GENETIC-DEFECT IN HUMANS DEFICIENT IN DEBRISOQUINE METABOLISM
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[J]. NATURE, 1988, 331 (6155) : 442 - 446
[10] FLECAINIDE - A PRELIMINARY REVIEW OF ITS PHARMACODYNAMIC PROPERTIES AND THERAPEUTIC EFFICACY
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HEEL, RC
[J]. DRUGS, 1985, 29 (01) : 1 - 33

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