FLUOXETINE-INDUCED SUICIDALITY, SEROTONIN, AND SEASONALITY

被引：15

作者：

BREWERTON, TD

机构：

[1] Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC

来源：

BIOLOGICAL PSYCHIATRY | 1991年 / 30卷 / 02期

关键词：

D O I：

10.1016/0006-3223(91)90173-J

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In spite of the complexities involved in suicide, fluoxetine has been prematurely and simplistically blamed for inducing this phenomenon. A variety of variables must be factored into such an interpretation. Nevertheless, given the complicated psychobiological circumstances involved, acute and rapid changes in serotonin (5-HT) function appear to be important to the understanding of changes in suicidal behavior. Such a mechanism may also explain the robust seasonal peak of suicides in spring.

引用

页码：190 / 196

页数：7

共 57 条

[1] THE EVIDENCE FOR 20 MG A DAY OF FLUOXETINE AS THE OPTIMAL DOSE IN THE TREATMENT OF DEPRESSION [J].