ABSENCE OF FOAMY VIRUS-DNA IN GRAVES-DISEASE

被引：42

作者：

SCHWEIZER, M

TUREK, R

REINHARDT, M

NEUMANNHAEFELIN, D

机构：

[1] UNIV FREIBURG,INST MED MIKROBIOL & HYG,VIROL ABT,D-79104 FREIBURG,GERMANY

[2] UNIV FREIBURG,RADIOL KLIN,NUKL MED ABT,D-79104 FREIBURG,GERMANY

来源：

AIDS RESEARCH AND HUMAN RETROVIRUSES | 1994年 / 10卷 / 05期

关键词：

D O I：

10.1089/aid.1994.10.601

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A report on the high prevalence of foamy virus DNA in lymphocytes from French patients with Graves' disease prompted us to investigate a similar cohort of 41 German patients. Using PCR amplification and Southern blot hybridization, we detected foamy virus DNA only in lymphocytes of two accidentally infected humans and five naturally infected monkeys, as well as in DNA samples from four Graves' disease patients investigated in the French study. However, we failed to detect foamy virus DNA in peripheral blood lymphocytes from any of the 41 Graves' disease patients of the German cohort. Thus, a causative role of foamy viruses in this thyroid disease is highly improbable.

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页码：601 / 605

页数：5

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