THE BIOLOGICAL BASIS OF MEDICAL-TREATMENT OF ENDOMETRIOSIS

被引：8

作者：

VENTURINI, PL

SEMINO, A

DECECCO, L

机构：

[1] Department of Gynecology and Obstetrics, University of Genoa School of Medicine, Genoa

来源：

GYNECOLOGICAL ENDOCRINOLOGY | 1995年 / 9卷 / 03期

关键词：

ENDOMETRIOSIS; HORMONAL THERAPY; HORMONES; IMMUNE SYSTEM;

D O I：

10.3109/09513599509160455

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Efficacy of medical treatment for the management of endometriosis has been documented in several trials, but clinical results cannot always be maintained after the suspension of treatment. Surgical treatment, either laparotomic or laparoscopic, is affected by tip to 20% in the recurrence of clinical symptoms after long-term follow-up. The appearance of endometriosis is heterogeneous, its functional status is variable and could lack hormone responsiveness. After medical, surgical or combined treatment the persistence of the failure of defence mechanisms accounts for the recurrence of disease. Unfortunately, all schemes to classify stages of endometriosis have so far failed to identify manifestations of the disease that respond in a predictable way to specific treatments. An analysis of the morphological appearance, implant biological activity and immune system involvement might better define the roles for medical management of endometriosis.

引用

页码：259 / 266

页数：8

共 43 条

[1]

Younger J.B., Endometriosis, Curr. Opin. Obstet. Gynecol, 5, pp. 333-339, (1993)

[2]

Sutton C.J.G., A critical evaluation of the management of pelvic pain, The Current Status of Endometriosis, pp. 437-446, (1992)

[3]

Waller K.G., Shaw R.W., Gonadotropin-releasing hormone analogue for the treatment of endometriosis: long-term follow-up, Fertil. Steril, 59, pp. 511-515, (1993)

[4]

Barbieri R.L., Evans S., Kistner R., Danazol in the treatment of endometriosis: analysis of 100 cases with a 4-year follow-up, Fertil. Steril, 37, pp. 737-742, (1982)

[5]

Biberoglu K.O., Behrman S.J., Dosage aspects of danazol therapy in endometriosis: short-term and long-term effectiveness, Am. J. Obstet. Gynecol, 139, pp. 645-654, (1981)

[6]

Fedele L., Bianchi S., Arcaini L., Vercellini P., Candiani G.B., Buserelin versus danazol in the treatment of endometriosis associated infertility, Am. J. Obstet. Gynecol, 161, pp. 871-876, (1989)

[7]

Zorn J.R., Mathieson J., Treatment of endometriosis, J. Gynecol. Obstet. Biol. Reprod, 19, pp. 600-603, (1990)

[8]

Nafarelin for endometriosis: a large-scale, danazol-controlled trial of efficacy and safety, with 1-year follow-up, Fertil. Steril, 57, pp. 514-522, (1992)

[9]

Fedele L., Bianchi S., Bocciolone L., Di Nola G., Franchi D., Buserelin acetate in the treatment of pelvic pain associated with minimal and mild endometriosis: a controlled study, Fertil. Steril, 59, pp. 516-521, (1993)

[10]

Dlugi A.M., Miller J.D., Knittle J., Lupron depot (leuprolide acetate for depot suspension) in the treatment of endometriosis: a randomized, placebo-controlled, double-blind study, Fertil. Steril, 54, pp. 419-427, (1990)

← 1 2 3 4 5 →