HERPES-SIMPLEX VIRUS-INFECTIONS OF THE CENTRAL-NERVOUS-SYSTEM - THERAPEUTIC AND DIAGNOSTIC CONSIDERATIONS

被引：216

作者：

WHITLEY, RJ

LAKEMAN, F

机构：

[1] UNIV ALABAMA, DEPT MICROBIOL, BIRMINGHAM, AL 35233 USA

[2] UNIV ALABAMA, DEPT MED, BIRMINGHAM, AL 35233 USA

来源：

CLINICAL INFECTIOUS DISEASES | 1995年 / 20卷 / 02期

关键词：

D O I：

10.1093/clinids/20.2.414

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Herpes simplex virus infections of the central nervous system remain a significant cause of morbidity and mortality, in spite of safe and efficacious antiviral therapy. Advances in the treatment of neonatal herpes and herpes simplex encephalitis with acyclovir have improved outcome, The application of polymerase chain reaction has allowed for the prompt and specific diagnosis of herpes simplex virus infections of the brain. This review summarizes our current knowledge on the pathogenesis, diagnosis, and treatment of herpes simplex virus infections of the brain, Opportunities for the future will be defined.

引用

页码：414 / 420

页数：7

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