EFFECTS OF ACYL-GROUPS AND ETHANOL RATIOS ON LIPASE-CATALYZED REGIOSELECTIVE DEACYLATION IN PERACYLATED METHYL GLYCOPYRANOSIDES

被引：8

作者：

HSIAO, KF

YANG, FL

WU, SH

WANG, KT

机构：

[1] NATL TAIWAN UNIV,DEPT CHEM,TAIPEI 10764,TAIWAN

[2] ACAD SINICA,INST BIOL CHEM,TAIPEI,TAIWAN

来源：

BIOTECHNOLOGY LETTERS | 1995年 / 17卷 / 09期

关键词：

D O I：

10.1007/BF00127435

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Regioselective ethanolysis of peracylated methyl beta, alpha-D-glucopyranoside and methyl alpha-D-mannopyranoside in anhydrous organic solvent (n-hexane/EtOH = 99/1) could afford 6-OH derivatives exclusively by Candida rugosa lipase (CPL). No 4 --> 6 acyl migration was observed in such an anhydrous solvent system. Substrates with propanoyl groups were more reactive than with acetyl groups on CRL-catalyzed reactions.

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页码：963 / 968

页数：6

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