APPLICATION OF DERIVATIZATION WITH PHENYLISOCYANATE TO CHROMATOGRAPHY OF PHENOLIC-COMPOUNDS (ANTIOXYDANTS)

被引：9

作者：

BAILLET, A

RAKOTOMANGA, S

FERRIER, D

PELLERIN, F

机构：

[1] Centre d'Études Pharmaceutiques, Laboratoire de Chimie Analytique, 92296 Chatenay-Malabry Cedex, Rue J. B. Clément

来源：

JOURNAL OF CHROMATOGRAPHY | 1990年 / 519卷 / 02期

关键词：

D O I：

10.1016/0021-9673(90)85162-O

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Application of derivatization with phenylisocyanate to chromatography of phenolic compounds (antioxydants). Phenylisocyanate reactivity towards compounds with mobile hydrogen (active hydrogen) has been applied to phenolic antioxidants, usually found in plastic polymers. The first part of this work studies the kinetics and the reaction mechanism in order to optimize its parameters. This method was then applied to the reversed-phase liquid chromatographic analysis of several phenolic antioxidants. The phenylcarbamates formed are detectable at 230 nm and the detection limit is lowered by a factor 5-10, depending on the compound, compared to direct detection at 280 nm. © 1990.

引用

页码：337 / 347

页数：11

共 12 条

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