THERAPEUTIC POTENTIAL OF CYTOKINE MANIPULATION

被引：64

作者：

HENDERSON, B

BLAKE, S

机构：

[1] UNIV LONDON UCL EASTMAN DENT HOSP, INST DENT SURG, LONDON WC1X 8LD, ENGLAND

[2] UNIV LONDON UCL EASTMAN DENT HOSP, INST DENT SURG, ORAL MED RES UNIT, LONDON WC1X 8LD, ENGLAND

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 1992年 / 13卷 / 04期

关键词：

D O I：

10.1016/0165-6147(92)90052-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Interleukin 1 is just one of a large, growing, collection of potent cytokines that are produced by a variety of cells and have a myriad of overlapping activities. Many of these cytokines have important pathophysiological actions in diseases ranging from rheumatoid arthritis to AIDS. Selective inhibition of the synthesis or of the action of specific cytokines may have therapeutic benefit. In this review, Brian Henderson and Simon Blake discuss the ways in which cytokine function could be manipulated pharmacologically for therapeutic benefit.

引用

页码：145 / 152

页数：8

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