ISOLATION AND CHARACTERIZATION OF GALANIN FROM SHEEP BRAIN

被引：38

作者：

SILLARD, R

LANGEL, U

JORNVALL, H

机构：

[1] HUDDINGE UNIV HOSP,CTR BIOTECHNOL,S-14186 HUDDINGE,SWEDEN

[2] UNIV STOCKHOLM,DEPT BIOCHEM,S-10691 STOCKHOLM,SWEDEN

[3] KAROLINSKA INST,DEPT CHEM I,S-10401 STOCKHOLM 60,SWEDEN

来源：

PEPTIDES | 1991年 / 12卷 / 04期

关键词：

NEUROPEPTIDE; GALANIN; SHEEP GALANIN; PEPTIDE AMIDE; SHEEP BRAIN;

D O I：

10.1016/0196-9781(91)90146-G

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Galanin is a well-known, naturally occurring peptide, which has been characterized from both cDNA sequences and direct peptide analysis. Previous structural studies have been made using intestinally derived material. This report concerns galanin isolation from sheep brain and its sequence determination. Sheep galanin shows great similarity to pig galanin, differing by one amino acid substitution, that being a histidine residue, as in cow and rat galanin, instead of tyrosine at position 26.

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页码：855 / 859

页数：5

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