STAPHYLOCOCCAL ENTEROTOXIN-A GENE (SEA) EXPRESSION IS NOT AFFECTED BY THE ACCESSORY GENE REGULATOR (AGR)

被引：59

作者：

TREMAINE, MT ^{[1
]}

BROCKMAN, DK ^{[1
]}

BETLEY, MJ ^{[1
]}

机构：

[1] UNIV WISCONSIN,MADISON,WI 53706

来源：

INFECTION AND IMMUNITY | 1993年 / 61卷 / 01期

关键词：

D O I：

10.1128/IAI.61.1.356-359.1993

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The goal of this work was to determine whether staphylococcal enterotoxin type A gene (sea) expression is regulated by an accessory gene regulator (agr). The Tn551 insertionally inactivated agr allele of Staphylococcus aureus ISP546 was transferred to three Sea+ S. aureus strains. Each of the Agr- strains produced as much staphylococcal enterotoxin A (SEA) as its parent strain. These results suggest that sea expression is regulated differently from that of seb, sec, and sed, which previously have been shown to require a functional agr system for maximal expression.

引用

页码：356 / 359

页数：4

共 32 条

[1]

ARVIDSON S, 1989, GENETIC TRANSFORMATI, P511

[2]

Arvidson S, 1990, MOL BIOL STAPHYLOCOC, P419

[3] GENETIC AND MOLECULAR ANALYSES OF THE GENE ENCODING STAPHYLOCOCCAL ENTEROTOXIN-D [J].