CLONING AND CHARACTERIZATION OF HUMAN TNF-ALPHA PROMOTER REGION

被引：75

作者：

TAKASHIBA, S

SHAPIRA, L

AMAR, S

VANDYKE, TE

机构：

[1] Department of Periodontology, Eastman Dental Center, Rochester

来源：

GENE | 1993年 / 131卷 / 02期

关键词：

RECOMBINANT DNA; SEQUENCING; POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR; TRANSCRIPTION FACTORS;

D O I：

10.1016/0378-1119(93)90314-S

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We report the sequence of a 1.2-kb human tumor necrosis factor alpha (TNFalpha) promoter region, which was cloned using PCR. The sequence has several variations from two previous reports and exhibits many potential DNA-binding sites specific to mammalian gene regulatory proteins inducible by lipopolysaccharides.

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收藏

页码：307 / 308

页数：2

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