APPLICATION OF POLYMERIC N-ACETYL-D-GLUCOSAMINE (CHITIN) TO VETERINARY PRACTICE

被引:88
作者
OKAMOTO, Y
MINAMI, S
MATSUHASHI, A
SASHIWA, H
SAIMOTO, H
SHIGEMASA, Y
TANIGAWA, T
TANAKA, Y
TOKURA, S
机构
[1] TOTTORI UNIV,FAC ENGN,DEPT MAT SCI,TOTTORI 680,JAPAN
[2] TOTTORI UNIV,FAC MED,DEPT BACTERIOL,YONAGO,TOTTORI 683,JAPAN
[3] HOKKAIDO UNIV,FAC SCI,DEPT POLYMER SCI,SAPPORO,HOKKAIDO 060,JAPAN
关键词
BIOMATERIAL; CHITIN; FILLING AGENT; WOUND DRESSING AGENT; WOUND HEALING;
D O I
10.1292/jvms.55.743
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
The sponge-, cotton-, and flake-type remedies made of chitin (chitin-sponge, chitin-cotton, and chitin-flake, respectively), and non-woven fabric of polyester (NWF) composited with chitin (chitin-NWF) were applied to various types of trauma, abscess, surgical tissue defect and herniorrhaphy in 147 clinical cases including 72 dogs, 38 cows, 33 cats, 2 rabbits, one monkey and one horse. Chitin-sponge was applied in 30 cases as filling agent of surgical tissue defect, and in 25 cases of trauma, 31 cases of abscess as wound dressing or tissue defect filling agent. In 77 out of 86 cases (89.5%), good healing developed. When chitin-sponge was buried in surgical tissue defects due to oncotomy in 20 cases, recurrence of the tumor developed in one case on one month post-operatively, but wag not recognized for 3-24 months in 19 cases. Chitin-NWF was applied in 2 cases of trauma and 12 cases of abscess as wound dressing or tissue defect filling agent, 6 cases as filling agent of surgical tissue defect, and 12 cases of umbilical hernia as prosthesis of suture site of hernia ring. In 28 out of 32 cases (87.5%), good healing developed. Chitin-cotton was applied in 8 cases of trauma and 12 cases of abscess as wound dressing or tissue defect filling agent. In 18 out of 20 cases (90.0%), good healing developed. Chitin-flake was applied in 9 cases of trauma as wound dressing or tissue defect filling agent. In 8 out of 9 cases (88.9%), good healing developed. In all cases, no side effects were observed.
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页码:743 / 747
页数:5
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