REGIOSELECTIVE ADDITION OF GRIGNARD-REAGENTS TO A 2-OXOPURINIUM SALT

被引：12

作者：

ANDRESEN, G

GUNDERSEN, LL

LUNDMARK, M

RISE, F

SUNDELL, S

机构：

[1] OSLO COLL,DEPT HLTH,PROGRAM PHARM,N-0167 OSLO,NORWAY

[2] UNIV OSLO,DEPT CHEM,N-0315 OSLO,NORWAY

[3] GOTHENBURG UNIV,DEPT MED BIOCHEM,S-41390 GOTHENBURG,SWEDEN

来源：

TETRAHEDRON | 1995年 / 51卷 / 12期

关键词：

D O I：

10.1016/0040-4020(95)00080-R

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of 6-ethoxy-1,3,6,7-tetrahydro-1,3,7-tribanzyl-2H-purin-2-one with trimethyl-chlorosilane gave a stable tribenzylated 2-oxopurinium salt, which selectively added Grignard reagents in the 6-position. The structure of the adducts were established from long range HETCOR NMR experiments.

引用

页码：3655 / 3664

页数：10

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