RECEPTORS FOR CALCITONIN, CALCITONIN-GENE-RELATED PEPTIDE, AMYLIN, AND ADRENOMEDULLIN

被引：27

作者：

MUFF, R

BORN, W

FISCHER, JA

机构：

[1] UNIV ZURICH, DEPT ORTHOPED SURG, CALCIUM METAB RES LAB, CH-8008 ZURICH, SWITZERLAND

[2] UNIV ZURICH, DEPT MED, CH-8008 ZURICH, SWITZERLAND

来源：

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | 1995年 / 73卷 / 07期

关键词：

ADRENOMEDULLIN; AMYLIN; CALCITONIN GENE RELATED PEPTIDE; CYCLIC AMP; RECEPTORS;

D O I：

10.1139/y95-133

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Calcitonin, calcitonin gene related peptide, amylin, and adrenomedullin are structurally related polypeptides characterized by a six or seven amino acid ring structure linked by a disulfide bridge and an amidated C-terminus. They exhibit overlapping biological actions as a result of cross-reactivity between the different receptors. In this article, the respective receptors and G-protein-coupled postreceptor events are reviewed in relation to some of the biological actions of the peptides.

引用

收藏

页码：963 / 967

页数：5

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