PHYTOHEMAGGLUTININ-INDUCED LYMPHOCYTE-TRANSFORMATION IN HUMANS RECEIVING DELTA-9-TETRAHYDROCANNABINOL

被引：49

作者：

LAU, RJ

TUBERGEN, DG

BARR, M

DOMINO, EF

BENOWITZ, N

JONES, RT

机构：

[1] UNIV MICHIGAN, DEPT PEDIAT & PHARMACOL, ANN ARBOR, MI 48109 USA

[2] UNIV CALIF SAN FRANCISCO, DEPT PSYCHIAT, SAN FRANCISCO, CA 94143 USA

来源：

SCIENCE | 1976年 / 192卷 / 4241期

关键词：

D O I：

10.1126/science.1265484

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Eight otherwise healthy male chronic marihuana smokers were hospitalized for a period of 30 days. Initially they received placebo, then a sustained dose of 210 mg of .DELTA.9-tetrahydrocannabinol (.DELTA.9-THC) per day for 18 days, followed by placebo. Lymphocyte responses to phytohemagglutinin [PHA] were examined during each of these periods. Neither the daily ingestion of marihuana extract containing 210 mg of .DELTA.9-THC for 18 days nor the history of chronic marihuana smoking had a depressive effect on the lymphocyte responses of these subjects to PHA.

引用

页码：805 / 807

页数：3

共 10 条

[1] MARIHUANA SMOKING - CARDIOVASCULAR EFFECTS IN MAN AND POSSIBLE MECHANISMS [J].