BRAIN MRI AND ELECTROPHYSIOLOGIC ABNORMALITIES IN PRECLINICAL AND CLINICAL ADRENOMYELONEUROPATHY

被引：56

作者：

AUBOURG, P

ADAMSBAUM, C

LAVALLARDROUSSEAU, MC

LEMAITRE, A

BOUREAU, F

MAYER, M

KALIFA, G

机构：

[1] HOP ST VINCENT DE PAUL, DEPT PEDIAT NEUROL, F-75674 PARIS 14, FRANCE

[2] HOP ST VINCENT DE PAUL, DEPT PEDIAT RADIOL, F-75674 PARIS 14, FRANCE

[3] HOP ST ANTOINE, DEPT NEUROPHYSIOL, F-75571 PARIS 12, FRANCE

来源：

NEUROLOGY | 1992年 / 42卷 / 01期

关键词：

D O I：

10.1212/WNL.42.1.85

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We describe the neurophysiologic abnormalities in 17 patients with clinical adrenomyeloneuropathy (AMN), an adult phenotype of X-linked adrenoleukodystrophy (ALD). These abnormalities also allowed the early recognition of the AMN phenotype in three asymptomatic boys with biochemically proven ALD. In 14/16 adult AMN patients, there were cerebral white matter abnormalities on MRI which were severe and comparable with cerebral ALD in four of the patients.

引用

页码：85 / 91

页数：7

共 36 条

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