MODIFICATION OF THE BINDING-AFFINITY OF PEPTIDE NUCLEIC-ACIDS (PNA) - PNA WITH EXTENDED BACKBONES CONSISTING OF 2-AMINOETHYL-BETA-ALANINE OR 3-AMINOPROPYLGLYCINE UNITS

被引：30

作者：

HYRUP, B

EGHOLM, M

ROLLAND, M

NIELSEN, PE

BERG, RH

BUCHARDT, O

机构：

[1] UNIV COPENHAGEN,HC ORSTED INST,CHEM LAB 2,MED BIOTECHNOL RES CTR,UNIV PK 5,DK-2100 COPENHAGEN,DENMARK

[2] PANUM INST,DEPT BIOCHEM B,DK-2200 COPENHAGEN N,DENMARK

[3] RISO NATL LAB,DEPT MAT,POLYMER RES LABS,DK-4000 ROSKILDE,DENMARK

来源：

关键词：

D O I：

10.1039/c39930000518

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The binding affinity between peptide nucleic acids (PNA) and DNA is reduced by incorporation of PNA units with extended backbones.

引用

页码：518 / 519

页数：2

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