IS CHICKEN GREEN-SENSITIVE CONE VISUAL PIGMENT A RHODOPSIN-LIKE PIGMENT - A COMPARATIVE-STUDY OF THE MOLECULAR-PROPERTIES BETWEEN CHICKEN GREEN AND RHODOPSIN

被引：71

作者：

SHICHIDA, Y

IMAI, H

IMAMOTO, Y

FUKADA, Y

YOSHIZAWA, T

机构：

[1] UNIV TOKYO, COLL ARTS & SCI, DEPT PURE & APPL SCI, TOKYO 153, JAPAN

[2] OSAKA SANGYO UNIV, FAC ENGN, DEPT INFORMAT SYST ENGN, DAITO, OSAKA 574, JAPAN

来源：

BIOCHEMISTRY | 1994年 / 33卷 / 31期

关键词：

D O I：

10.1021/bi00197a002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chicken green is a visual pigment present in chicken green-sensitive cones and has an amino acid sequence more similar than any other cone visual pigments to the rod visual pigments, rhodopsins. Here we have investigated the molecular properties of chicken green and compared them with those of rhodopsin to elucidate whether or not chicken green is a rhodopsin-like pigment. While chicken green has a molecular extinction coefficient and a photosensitivity very similar to those of rhodopsin, it displays faster regeneration from 11-cis-retinal and opsin and faster formation and decay of the physiologically active meta II intermediate than rhodopsin. These differences correlate with the physiological difference between cones and rods. Thus in spite of the similarity in amino acid sequence, chicken green displays molecular properties required for a cone visual pigment that are clearly different from those of rhodopsin.

引用

页码：9040 / 9044

页数：5

共 32 条

[1] VISUAL PIGMENTS IN SINGLE RODS + CONES OF HUMAN RETINA - DIRECT MEASUREMENTS REVEAL MECHANISMS OF HUMAN NIGHT + COLOR VISION [J].