A NEW SYNTHETIC ROUTE TO METHYLENOMYCIN B VIA RHODIUM(II)-MEDIATED DECOMPOSITION OF ALPHA,BETA-UNSATURATED ALPHA'-DIAZOKETONES

被引：7

作者：

CECCHERELLI, P ^{[1
]}

CURINI, M ^{[1
]}

MARCOTULLIO, MC ^{[1
]}

ROSATI, O ^{[1
]}

机构：

[1] UNIV PERUGIA,FAC FARM,INST CHIM ORGAN,I-06100 PERUGIA,ITALY

来源：

SYNTHETIC COMMUNICATIONS | 1991年 / 21卷 / 01期

关键词：

D O I：

10.1080/00397919108020785

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new synthesis of methylenomycin B, involving Rh (II)-catalyzed, intramolecular carbon-hydrogen insertion of diazoketone 2c, derived from 2,3-dimethyl-2-butenoic acid 2b, is reported.

引用

页码：17 / 23

页数：7

共 29 条

[1] METHYLENOMYCIN-B - AN EFFICIENT SYNTHESIS FROM (2-BUTYNE)HEXACARBONYLDICOBALT
BILLINGTON, DC
PAUSON, PL
[J]. ORGANOMETALLICS, 1982, 1 (12) : 1560 - 1561
[2] BRANDE EA, 1955, J CHEM SOC, P3331
[3] SYNTHESIS OF CYCLOPENTANOID NATURAL-PRODUCTS VIA VINYL PHOSPHONIUM SALTS
CAMERON, AG
HEWSON, AT
OSAMMOR, MI
[J]. TETRAHEDRON LETTERS, 1984, 25 (21) : 2267 - 2270
[4] A TOTAL SYNTHESIS OF METHYLENOMYCIN-B
CAMPS, F
COLL, J
MORETO, JM
TORRAS, J
[J]. TETRAHEDRON LETTERS, 1985, 26 (51) : 6397 - 6398
[5] A NEW, GENERAL CYCLOPENTENONE SYNTHESIS
CECCHERELLI, P
CURINI, M
MARCOTULLIO, MC
ROSATI, O
WENKERT, E
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (01) : 311 - 315
[6] SYNTHESIS AND OXIDIZING CYCLIZATION OF 2,3,5-TRIENE-1-OLS IN 5-HYDROXYALKYL-2-CYCLOPENTENE-1-ONES
DOUTHEAU, A
SARTORETTI, J
GORE, J
[J]. TETRAHEDRON, 1983, 39 (19) : 3059 - 3065
[7] GALLAGHE.G, 1974, SYNTHESIS-STUTTGART, P122
[8] NEW ANTIBIOTICS, METHYLENOMYCINS-A AND B .1. PRODUCING ORGANISM, FERMENTATION AND ISOLATION, BIOLOGICAL-ACTIVITIES AND PHYSICAL AND CHEMICAL PROPERTIES
HANEISHI, T
KITAHARA, N
TAKIGUCHI, Y
ARAI, M
SUGAWARA, S
[J]. JOURNAL OF ANTIBIOTICS, 1974, 27 (06) : 386 - 392
[9] HO TL, 1977, SYNTHESIS-STUTTGART, P417
[10] FORMAL SYNTHESIS OF METHYLENOMYCIN-B
HO, TL
[J]. SYNTHETIC COMMUNICATIONS, 1983, 13 (05) : 435 - 439

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