INHIBITION OF METALLOPROTEINASE BY FUTOENONE DERIVATIVES

被引：17

作者：

YEH, LA ^{[1
]}

CHEN, J ^{[1
]}

BACULI, F ^{[1
]}

GINGRICH, DE ^{[1
]}

SHEN, TY ^{[1
]}

机构：

[1] UNIV VIRGINIA,DEPT CHEM,CHARLOTTESVILLE,VA 22901

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1995年 / 5卷 / 15期

关键词：

D O I：

10.1016/0960-894X(95)00282-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Futoenone and a series of its derivatives have shown inhibitory activities against matrix metalloproteinases. The molecular modelings of these compounds indicate the preferred binding of the P2' site of the enzymes.

引用

页码：1637 / 1642

页数：6

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