CARDIAC MYXOMAS - IMMUNOHISTOCHEMICAL STUDY OF BENIGN AND MALIGNANT VARIANTS

被引：22

作者：

CURSCHELLAS, E ^{[1
]}

TOIA, D ^{[1
]}

BORNER, M ^{[1
]}

MIHATSCH, MJ ^{[1
]}

GUDAT, F ^{[1
]}

机构：

[1] UNIV BASEL,KANTONSSPITAL,DEPT ONCOL,CH-4051 BASEL,SWITZERLAND

来源：

VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY | 1991年 / 418卷 / 06期

关键词：

CARDIAC MYXOMA; IMMUNOHISTOCHEMISTRY; HISTOGENESIS;

D O I：

10.1007/BF01606497

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

Immunohistochemical investigation of 11 cardiac myxomas (CMs) including one malignant metastasizing CM showed a co-expression of epithelial (lu-5 and CAM 5.2), mesenchymal (vimentin) and neuroendocrine antigens (neuron-specific enolase) in all tumour cells. Factor VIII was found in the endothelial cells of capillaries only. In the subendocardium of fetal heart tissue close to the foramen ovale myofibroblasts reacting with the panepithelial antibody lu-5 were detected. We conclude that CMs are neoplasms that may develop from embryonic cell remnants.

引用

页码：485 / 491

页数：7

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