BENZODIAZEPINE RECEPTOR-BINDING AND ANTICONFLICT ACTIVITY IN A SERIES OF 3,6-DISUBSTITUTED PYRIDAZINO[4,3-C]ISOQUINOLINES DEVOID OF ANTICONVULSANT PROPERTIES

被引：19

作者：

TOJA, E

TARZIA, G

BARONE, D

LUZZANI, F

GALLICO, L

机构：

[1] LEPETIT RES CTR, DEPT CHEM, I-20158 MILANO, ITALY

[2] LEPETIT RES CTR, DEPT PHARMACOL, I-20158 MILANO, ITALY

来源：

关键词：

D O I：

10.1021/jm00147a034

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1314 / 1319

页数：6

共 25 条

[1] ALLEN GR, 1978, Patent No. 4112095
[2] BENFENATI F, 1984, 1982 P NATO ADV STUD, P41
[3] BERGER FM, 1952, J PHARMACOL EXP THER, V104, P468
[4] BOISSIER JR, 1960, THERAPIE, V15, P1170
[5] Colton T., 1974, STAT MED, P189
[6] A NOTE ON A SIMPLE APPARATUS FOR DETECTING NEUROLOGICAL DEFICIT IN RATS AND MICE
DUNHAM, NW
MIYA, TS
[J]. JOURNAL OF THE AMERICAN PHARMACEUTICAL ASSOCIATION, 1957, 46 (03): : 208 - 209
[7] Finney D.J, 1952, PROBIT ANAL
[8] SELECTIVE ANTAGONISTS OF BENZODIAZEPINES
HUNKELER, W
MOHLER, H
PIERI, L
POLC, P
BONETTI, EP
CUMIN, R
SCHAFFNER, R
HAEFELY, W
[J]. NATURE, 1981, 290 (5806) : 514 - 516
[9] MULTIPLE BENZODIAZEPINE RECEPTORS - EVIDENCE OF A DISSOCIATION BETWEEN ANTI-CONFLICT AND ANTICONVULSANT PROPERTIES BY PK8165 AND PK9084 (2 QUINOLINE DERIVATIVES)
LEFUR, G
MIZOULE, J
BURGEVIN, MC
FERRIS, O
HEAULME, M
GAUTHIER, A
GUEREMY, C
UZAN, A
[J]. LIFE SCIENCES, 1981, 28 (13) : 1439 - 1448
[10] SYNTHETIC NON-BENZODIAZEPINE LIGAND FOR BENZODIAZEPINE RECEPTORS - PROBE FOR INVESTIGATING NEURONAL SUBSTRATES OF ANXIETY
LIPPA, AS
COUPET, J
GREENBLATT, EN
KLEPNER, CA
BEER, B
[J]. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 1979, 11 (01) : 99 - 106