A FIBROBLAST ELONGATION-FACTOR PURIFIED FROM COLON-CARCINOMA CELLS SHARES SEQUENCE IDENTITY WITH TIMP-1

被引：17

作者：

AGREZ, MV

MELDRUM, CJ

SIM, ATR

AEBERSOLD, RH

CLARK, IM

CAWSTON, TE

BURNS, GF

机构：

[1] UNIV BRITISH COLUMBIA,BIOMED RES CTR,VANCOUVER,BC,CANADA

[2] UNIV BRITISH COLUMBIA,DEPT BIOCHEM,VANCOUVER,BC,CANADA

[3] ADDENBROOKES HOSP,RHEUMATOL UNIT,CAMBRIDGE,ENGLAND

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1995年 / 206卷 / 02期

关键词：

D O I：

10.1006/bbrc.1995.1084

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have previously reported that human colon cancer cells secrete a factor(s) which induces elongation of colon fibroblasts in vitro. Isolation of this factor led to the identification of a 55kD protein with fibroblast stretching activity. Two internal amino acid sequences identified in this protein (YEI; GFQALGDAADI) share complete homology with tissue inhibitor of metalloproteinase (TIMP-1). (C) 1995 Academic Press, Inc.

引用

页码：590 / 600

页数：11

共 14 条

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